US-Based Startups
AeroShield Materials
FOUNDER
INDUSTRY/SECTOR
Building Materials & Energy Efficiency
HQ
Waltham, Massachusetts
WEBSITE
AeroShield Materials is an MIT spinout that manufactures the world’s most insulating, lightest, transparent materials. AeroShield enables the next generation of high-performance and energy-efficient products across windows, freezers, automotive, aerospace, and more.
Brightlight Photonics
FOUNDER
INDUSTRY/SECTOR
Photonics & Quantum
HQ
Cambridge, Massachusetts
Brightlight Photonics develops on-chip lasers and amplifiers made from titanium-doped thin-film sapphire and custom photonic solutions in the visible and ultraviolet, from bare chips to fiber-interfaced devices.
CavilinQ
FOUNDER
INDUSTRY/SECTOR
Quantum Hardware
HQ
Cambridge, Massachusetts
WEBSITE
CavilinQ provides the most economical, clean, and continuous path to next-generation fault-tolerant quantum computers and quantum data centers.
ESTAT Actuation
FOUNDER
INDUSTRY/SECTOR
Robotics & Actuation
HQ
Pittsburgh, Pennsylvania
WEBSITE
ESTAT Actuation builds ESTAT clutches are 10x lighter, 10x more compact, and 1000x more efficient than conventional clutches. ESTAT clutches use electroadhesion to “glue” and “unglue” surfaces, enabling new actuator designs for mobile robots, logistics robots, wearable robots and manufacturing systems.
FlowCellutions
FOUNDER
INDUSTRY/SECTOR
Grid Storage & Battery Diagnostics
HQ
Houston, Texas
WEBSITE
FlowCellutions builds state-of-health diagnostics, proprietary sensing, and predictive maintenance software for grid-scale/flow batteries to extend battery life, prevent critical-infrastructure outages, and reduce O&M/OPEX for battery manufacturers, data centers, hospitals, and grid operators.
Gallox Semiconductors
FOUNDER
INDUSTRY/SECTOR
Semiconductors & Photonics
HQ
Ithaca, New York
WEBSITE
Gallox Semiconductors develops ultrawide bandgap gallium oxide (Ga2O3) transistors and diodes that eliminate that inefficiency, enable more powerful electronics circuitry, and reduce a system’s size, weight, and engineering complexity with target applications including data center, EV charging, satellites, drones, and aircraft.
Helix Earth
FOUNDER
INDUSTRY/SECTOR
HVAC & Climate Tech
HQ
Houston, Texas
WEBSITE
Helix Earth develops the first retrofit system that gives commercial buildings fresher air, lower humidity, and lower energy costs without replacing a thing. Powered by NASA technology.
LiftOFF Technology
FOUNDER
INDUSTRY/SECTOR
Energy Storage & Batteries
HQ
Somerville/Boston, Massachusetts
WEBSITE
LiftOFF Technology develops next-generation battery cells that deliver up to 3× higher energy density with improved safety, using abundant, domestically available materials. Their drop-in technology scales on existing lithium-ion manufacturing infrastructure. Backed by Breakthrough Energy and the U.S. Department of Energy’s Genesis Mission, they accelerate technology development through AI-driven R&D.
MacroCycle Technologies
FOUNDER
INDUSTRY/SECTOR
Sustainability & Circular Materials
HQ
Cambridge, Massachusetts
WEBSITE
MacroCycle Technologies’ patented technology recycles plastic and polyester waste into virgin-grade MacroCycle PET or polyester resins to improve companies’ ability to meet sustainability goals, including satisfaction of PCR Regulations, elimination of landfill and ocean-bound plastics, and lowered Scope 3 emissions, all without a green premium.
Oleo
FOUNDER
INDUSTRY/SECTOR
Biofuels & Biomanufacturing
HQ
Berkeley, California
WEBSITE
Oleo delivers reliable, lower-carbon fuel feedstocks at price parity with conventional alternatives. By converting waste into economical feedstocks, Oleo unlocks new production capacity for profitable advanced fuel pathways, ultimately, accelerating the transition to cleaner fuels.
Pascal
FOUNDER
INDUSTRY/SECTOR
HVAC & Sustainable Cooling
HQ
Cambridge, Massachusetts
Pascal is commercializing solid refrigerants as cleaner, more efficient alternatives to gas refrigerants in a wide variety of heating, cooling, and refrigeration systems. Solid refrigerants eliminate the greenhouse gas emissions and air and water pollution caused by leaking gas refrigerants while improving the energy efficiency of refrigeration systems by at least 20%, all at similar costs to conventional systems. Pascal has fully integrated its solid refrigerant into a commercial refrigerator and is actively developing a solid refrigerant beverage cooler, in partnership with a major beverage brand.
Phase3D
FOUNDER
INDUSTRY/SECTOR
Additive Manufacturing & Inspection
HQ
Chicago, Illinois
WEBSITE
Phase3D is on a mission to empower the additive manufacturing industry by offering a trusted part quality assurance technology. We produce quantitative measurements of the AM process using Fringe Projection to correlate build anomalies to material properties and part quality for all AM applications.
Sensate Robotics
FOUNDER
INDUSTRY/SECTOR
Robotics & Tactile Sensing
HQ
Los Angeles, California
WEBSITE
Sensate Roboticsâ„¢ builds multimodal tactile sensors and robotic gripping systems that give machines a true sense of touch and automate the work where irregular objects, quality judgment, and delicate handling meet a hard labor constraint. The company’s debut is in fruit handling, where the need is urgent, and the work still depends on human hands. The same technology reaches every industry where touch is the missing input.
SirenOpt
FOUNDER
INDUSTRY/SECTOR
Advanced Manufacturing & Materials Characterization
HQ
San Leandro, California
WEBSITE
SirenOpt provides real-time, non-destructive materials characterization for advanced manufacturing using cold atmospheric plasma and AI through its PlasmaSens platform, targeting batteries, semiconductors, aerospace, power generation and other thin-film/coating manufacturers.
VioNano Innovations
FOUNDER
INDUSTRY/SECTOR
Semiconductor Materials
HQ
Cambridge, Massachusetts
WEBSITE
VioNano develops specialty polymeric materials for advanced semiconductor manufacturing, helping chipmakers build smaller, faster, and more cost-effective chips for AI and quantum infrastructure.













